Opinion Paper

Addressing the need for an operational research framework for Africa

Isaac A. Choge, Neema W. Kamara, Merawi T. Aragaw, Nicaise Ndembi, Landry D. D. Tsague
Journal of Public Health in Africa | Vol 17, No 1 | a1491 | DOI: https://doi.org/10.4102/jphia.v17i1.1491 | © 2026 Isaac A. Choge, Neema W. Kamara, Merawi T. Aragaw, Nicaise Ndembi, Landry D. Tsague | This work is licensed under CC Attribution 4.0
Submitted: 09 July 2025 | Published: 06 February 2026

About the author(s)

Isaac A. Choge, Department of Emergency Preparedness and Response (EPR), Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia
Neema W. Kamara, Department of Emergency Preparedness and Response (EPR), Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia
Merawi T. Aragaw, Department of Surveillance and Disease Intelligence, Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia
Nicaise Ndembi, International Vaccine Institute, Kigali, Rwanda
Landry D. D. Tsague, Department of Primary Health Care, Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia

Abstract

Africa Centres for Disease Control and Prevention (CDC), which supports all 55 member states (MS) in Africa, was established to strengthen the capacity and capability of Africa’s public health institutions to detect and respond quickly and effectively to disease threats and outbreaks based on science, policy, and data-driven interventions and programmes. This function is drawn from the African Union (AU) Assembly of Heads of State and Government, which adopted the statute of the Africa CDC in January 2016 and implemented it in mid-2017. Africa desperately needs an operational research (OR) framework for all 55 MS. The OR framework’s strategic aim is to strengthen the capacity to initiate, design and implement OR during disease outbreaks and emergencies. The framework, with support from the Africa CDC, will therefore provide a concise guide to institutional structures, procedures and standards, as well as an outline of methodologies and tools for conducting OR that is context-specific, while promoting the use of generated evidence for policy and decision makers. Drawing on expert reviews, we present here the need for the OR framework and the process of its development for research during public health emergencies in Africa.

Keywords

Africa CDC; emergencies; operational research; implementation research; diseases threats; prevention.

Sustainable Development Goal

Goal 3: Good health and well-being

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