A brief review on features of falciparum malaria during pregnancy


Submitted: 24 March 2017
Accepted: 17 August 2017
Published: 31 December 2017
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Malaria in pregnancy is a serious public health problem in tropical areas. Frequently, the placenta is infected by accumulation of Plasmodium falciparum-infected erythrocytes in the intervillous space. Falciparum malaria acts during pregnancy by a range of mechanisms, and chronic or repeated infection and co-infections have insidious effects. The susceptibility of pregnant women to malaria is due to both immunological and humoral changes. Until a malaria vaccine becomes available, the deleterious effects of malaria in pregnancy can be avoided by protection against infection and prompt treatment with safe, effective antimalarial agents; however, concurrent infections such as with HIV and helminths during pregnancy are jeopardizing malaria control in sub-Saharan Africa.

Supporting Agencies

Institut Pasteur of Bangui

Manirakiza, A., Serdouma, E., Ngbalé, R. N., Moussa, S., Gondjé, S., Mbetid Degana, R., Banthas Bata, G. G., Moyen, J. M., Delmont, J., Grésenguet, G., & Sepou, A. (2017). A brief review on features of falciparum malaria during pregnancy. Journal of Public Health in Africa, 8(2). https://doi.org/10.4081/jphia.2017.668

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